XRCC2 and XRCC3 Regulate the Balance between Short- and Long-Tract Gene Conversions between Sister Chromatids
نویسندگان
چکیده
منابع مشابه
FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids
The FANCJ DNA helicase is linked to hereditary breast and ovarian cancers as well as bone marrow failure disorder Fanconi anemia (FA). Although FANCJ has been implicated in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR), the molecular mechanism underlying the tumor suppressor functions of FANCJ remains obscure. Here, we demonstrate that FANCJ deficient human and ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2009
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.01406-08